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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL365680
Molecular formula	C18H20Cl2FNO5
IUPAC name	(1R,2R,3R,5R,6R)-2-amino-3-[(1R)-1-(3,4-dichlorophenyl)butoxy]-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Molecular weight	420.258
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	0.6
Synonyms	BDBM50151439 (1R,2R,3R,5R,6R)-2-Amino-3-[(R)-1-(3,4-dichloro-phenyl)-butoxy]-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
Inchi Key	DMWXAHQIYDWDOA-VHFIOLPJSA-N
Inchi ID	InChI=1S/C18H20Cl2FNO5/c1-2-3-12(8-4-5-10(19)11(20)6-8)27-13-7-9-14(17(9,21)15(23)24)18(13,22)16(25)26/h4-6,9,12-14H,2-3,7,22H2,1H3,(H,23,24)(H,25,26)/t9-,12-,13-,14+,17-,18+/m1/s1
PubChem CID	11339150
ChEMBL	CHEMBL365680
IUPHAR	N/A
BindingDB	50151439
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
64092	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559270	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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