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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL476791
Molecular formula	C27H27N3O
IUPAC name	1-methyl-2-[[(1R,5S)-6-[(3-phenylphenoxy)methyl]-3-azabicyclo[3.1.0]hexan-3-yl]methyl]benzimidazole
Molecular weight	409.533
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.9
Synonyms	2-[(1R,5S)-6-(Biphenyl-3-yloxymethyl)-3-aza-bicyclo[3.1.0]hex-3-ylmethyl]-1-methyl-1H-benzoimidazole BDBM50263354
Inchi Key	DJHVINVBCJUYRT-VSGJHWFKSA-N
Inchi ID	InChI=1S/C27H27N3O/c1-29-26-13-6-5-12-25(26)28-27(29)17-30-15-22-23(16-30)24(22)18-31-21-11-7-10-20(14-21)19-8-3-2-4-9-19/h2-14,22-24H,15-18H2,1H3/t22-,23+,24?
PubChem CID	44578904
ChEMBL	CHEMBL476791
IUPHAR	N/A
BindingDB	50263354
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
61456	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
559176	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872

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