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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1629865
Molecular formula	C22H16F3N3O
IUPAC name	4-[3-(2-methylpyridin-4-yl)phenyl]-8-(trifluoromethyl)-1,3-dihydro-1,5-benzodiazepin-2-one
Molecular weight	395.385
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.3
Synonyms	4-(3-(2-methylpyridin-4-yl)phenyl)-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one BDBM50333000 DFWDFOZNVALGES-UHFFFAOYSA-N 4-[3-(2-Methyl-pyridin-4-yl)-phenyl]-8-trifluoromethyl-1,3-dihydro benzo[b][1,4]diazepin-2-one SCHEMBL5563741
Inchi Key	DFWDFOZNVALGES-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H16F3N3O/c1-13-9-15(7-8-26-13)14-3-2-4-16(10-14)19-12-21(29)28-20-11-17(22(23,24)25)5-6-18(20)27-19/h2-11H,12H2,1H3,(H,28,29)
PubChem CID	11211597
ChEMBL	CHEMBL1629865
IUPHAR	N/A
BindingDB	50333000
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58963	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
58964	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
58962	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879

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