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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL169274
Molecular formula	C23H17ClF3N3OS
IUPAC name	(4S,5R)-N-[4-chloro-3-(trifluoromethyl)phenyl]-3-oxo-4,5-diphenylpyrazolidine-1-carbothioamide
Molecular weight	475.914
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	5.7
Synonyms	BDBM50281731 LY-294920 (4S,5R)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothioic acid (4-chloro-3-trifluoromethyl-phenyl)-amide SCHEMBL8846934
Inchi Key	DFOIEDQSOJASSS-PMACEKPBSA-N
Inchi ID	InChI=1S/C23H17ClF3N3OS/c24-18-12-11-16(13-17(18)23(25,26)27)28-22(32)30-20(15-9-5-2-6-10-15)19(21(31)29-30)14-7-3-1-4-8-14/h1-13,19-20H,(H,28,32)(H,29,31)/t19-,20-/m0/s1
PubChem CID	44382706
ChEMBL	CHEMBL169274
IUPHAR	N/A
BindingDB	50281731
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58736	Cholecystokinin receptor type A	P30551	Cckar	Rattus norvegicus (Rat)	444
58737	Gastrin/cholecystokinin type B receptor	P56481	Cckbr	Mus musculus (Mouse)	453

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