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Name | Gastrin/cholecystokinin type B receptor |
---|---|
Species | Mus musculus (Mouse) |
Gene | Cckbr |
Synonym | CHOLREC Cholecystokinin-2 receptor CCK2-R CCK2 receptor CCK-BR [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 453 |
Amino acid sequence | MDLLKLNRSLQGPGPGSGSSLCRPGVSLLNSSSAGNLSCETPRIRGTGTRELELTIRITLYAVIFLMSVGGNVLIIVVLGLSRRLRTVTNAFLLSLAVSDLLLAVACMPFTLLPNLMGTFIFGTVICKAVSYLMGVSVSVSTLNLAAIALERYSAICRPLQARVWQTRSHAARVILATWLLSGLLMVPYPVYTVVQPVGPRILQCMHLWPSERVQQMWSVLLLILLFFIPGVVMAVAYGLISRELYLGLRFDGDNDSETQSRVRNQGGLPGGAAAPGPVHQNGGCRHVTSLTGEDSDGCYVQLPRSRLEMTTLTTPTTGPGPGPRPNQAKLLAKKRVVRMLLVIVLLFFVCWLPVYSANTWRAFDGPGARRALAGAPISFIHLLSYTSACANPLVYCFMHRRFRQACLDTCARCCPRPPRARPRPLPDEDPPTPSIASLSRLSYTTISTLGPG |
UniProt | P56481 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2854 |
IUPHAR | 77 |
DrugBank | N/A |
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GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
6 | ![]() | C28H32N4O5 | 504.587 | 5 / 4 | 3.4 | No |
75 | ![]() | C34H31FN4O4 | 578.644 | 7 / 1 | 6.3 | No |
630 | ![]() | C25H20BrN3O2 | 474.358 | 3 / 1 | 5.1 | No |
1156 | ![]() | C24H18FN3O | 383.426 | 3 / 1 | 4.5 | Yes |
441718 | ![]() | C29H39N3O5 | 509.647 | 5 / 5 | N/A | No |
441719 | ![]() | C29H39N3O5 | 509.647 | 5 / 5 | N/A | No |
1351 | ![]() | C29H39N3O5 | 509.647 | 5 / 5 | N/A | No |
3058 | ![]() | C30H36N4O | 468.645 | 3 / 3 | 7.4 | No |
3218 | ![]() | C33H40N4O5 | 572.706 | 6 / 5 | 4.8 | No |
7046 | ![]() | C24H21N7O2 | 439.479 | 5 / 3 | 3.0 | Yes |
7731 | ![]() | C45H56N6O12 | 872.973 | 14 / 11 | N/A | No |
8258 | ![]() | C39H44N4O5S | 680.864 | 6 / 5 | 6.7 | No |
8453 | ![]() | C35H41FN4O7S | 680.792 | 8 / 2 | 4.0 | No |
553289 | ![]() | C37H49N7O9S | 767.899 | 10 / 8 | 2.2 | No |
10231 | ![]() | C34H45N5O7 | 635.762 | 7 / 6 | 4.3 | No |
14564 | ![]() | C42H45ClN6O8 | 797.306 | 8 / 7 | 5.4 | No |
15248 | ![]() | C28H33N3O6 | 507.587 | 6 / 2 | 2.9 | No |
15361 | ![]() | C47H47N3O8 | 781.906 | 8 / 5 | 6.6 | No |
16634 | ![]() | C40H47N5O6S | 725.905 | 7 / 5 | 5.4 | No |
16635 | ![]() | C40H47N5O6S | 725.905 | 7 / 5 | 5.4 | No |
16990 | ![]() | C34H38N2O4 | 538.688 | 4 / 2 | 5.0 | No |
18782 | ![]() | C36H41N5O5 | 623.754 | 5 / 4 | 5.3 | No |
18784 | ![]() | C36H41N5O5 | 623.754 | 5 / 4 | 5.3 | No |
20596 | ![]() | C26H23N3O | 393.49 | 2 / 1 | 5.2 | No |
22485 | ![]() | C34H43N5O7 | 633.746 | 7 / 5 | 3.8 | No |
23701 | ![]() | C24H21BrN4O3 | 493.361 | 4 / 2 | 4.9 | Yes |
23798 | ![]() | C45H45N3O5 | 707.871 | 5 / 4 | 7.1 | No |
24527 | ![]() | C42H47N5O8 | 749.865 | 8 / 6 | 5.8 | No |
24991 | ![]() | C37H50N2O3 | 570.818 | 3 / 2 | 8.9 | No |
27777 | ![]() | C23H21N5O3 | 415.453 | 4 / 3 | 3.5 | Yes |
28070 | ![]() | C47H47N3O7 | 765.907 | 7 / 5 | 6.8 | No |
29951 | ![]() | C26H22BrN3O | 472.386 | 2 / 1 | 5.9 | No |
32454 | ![]() | C28H38N4O3 | 478.637 | 4 / 3 | 5.1 | No |
32775 | ![]() | C28H28N4O5 | 500.555 | 6 / 2 | 4.2 | No |
32948 | ![]() | C34H43N3O4 | 557.735 | 5 / 2 | 6.1 | No |
32960 | ![]() | C41H43N5O7 | 717.823 | 8 / 5 | 5.8 | No |
33254 | ![]() | C45H53N7O6 | 787.962 | 8 / 4 | 5.4 | No |
35415 | ![]() | C31H39N3O3 | 501.671 | 4 / 3 | 7.5 | No |
38497 | ![]() | C28H24N2O3 | 436.511 | 3 / 3 | 4.1 | Yes |
39119 | ![]() | C35H41N7O4S | 655.818 | 7 / 5 | 5.1 | No |
40394 | ![]() | C30H38N2O6 | 522.642 | 6 / 5 | 3.7 | No |
41096 | ![]() | C27H24BrN3O | 486.413 | 2 / 1 | 6.3 | No |
443338 | ![]() | C34H44N4O7 | 620.747 | 7 / 6 | N/A | No |
41710 | ![]() | C25H37N3O3 | 427.589 | 4 / 3 | 3.6 | Yes |
42660 | ![]() | C40H46N4O5 | 662.831 | 5 / 5 | 6.4 | No |
43795 | ![]() | C32H36N2O5 | 528.649 | 5 / 1 | 5.3 | No |
44891 | ![]() | C30H39N3O7 | 553.656 | 7 / 3 | 3.7 | No |
46611 | ![]() | C37H37N5O7 | 663.731 | 8 / 6 | 4.9 | No |
443529 | ![]() | C32H40N4O6 | 576.694 | 6 / 5 | 4.1 | No |
46857 | ![]() | C32H40N4O6 | 576.694 | 6 / 5 | 4.1 | No |
46953 | ![]() | C46H37N3O7 | 743.816 | 7 / 5 | 6.5 | No |
47205 | ![]() | C24H22N6O6S2 | 554.596 | 9 / 6 | 4.4 | No |
47908 | ![]() | C31H35N3O3 | 497.639 | 4 / 3 | 7.3 | No |
51156 | ![]() | C34H34FN5O7 | 643.672 | 9 / 6 | 5.0 | No |
52826 | ![]() | C26H33N3O3 | 435.568 | 4 / 3 | 6.1 | No |
52901 | ![]() | C32H31N5O2 | 517.633 | 5 / 0 | 5.7 | No |
53470 | ![]() | C38H37N3O7S | 679.788 | 8 / 5 | 6.3 | No |
57696 | ![]() | C32H35N3O5 | 541.648 | 5 / 4 | 5.7 | No |
58645 | ![]() | C25H23BrN4O2S | 523.449 | 4 / 2 | 5.2 | No |
58737 | ![]() | C23H17ClF3N3OS | 475.914 | 5 / 2 | 5.7 | No |
58739 | ![]() | C23H17ClF3N3OS | 475.914 | 5 / 2 | 5.7 | No |
58740 | ![]() | C23H17ClF3N3OS | 475.914 | 5 / 2 | 5.7 | No |
59860 | ![]() | C36H43N9O5 | 681.798 | 8 / 6 | 3.5 | No |
59861 | ![]() | C36H43N9O5 | 681.798 | 8 / 6 | 3.5 | No |
60692 | ![]() | C35H42N4O5 | 598.744 | 5 / 5 | 4.5 | No |
60891 | ![]() | C44H58N6O10 | 830.98 | 12 / 12 | N/A | No |
62614 | ![]() | C24H29N3O3 | 407.514 | 4 / 3 | 5.3 | No |
62724 | ![]() | C38H38N4O7 | 662.743 | 7 / 6 | 5.5 | No |
64194 | ![]() | C25H23N5O5 | 473.489 | 6 / 4 | 3.5 | Yes |
64233 | ![]() | C26H23N3O3 | 425.488 | 4 / 3 | 5.0 | Yes |
64290 | ![]() | C42H47N7O5 | 729.882 | 7 / 4 | 5.2 | No |
444229 | ![]() | C32H38N4O6 | 574.678 | 6 / 5 | 4.5 | No |
64478 | ![]() | C32H38N4O6 | 574.678 | 6 / 5 | 4.5 | No |
64524 | ![]() | C35H30F4N4O6 | 678.641 | 12 / 2 | N/A | No |
65999 | ![]() | C34H39N3O5 | 569.702 | 5 / 3 | 5.6 | No |
66002 | ![]() | C34H39N3O5 | 569.702 | 5 / 3 | 5.6 | No |
66266 | ![]() | C24H23N3O5 | 433.464 | 5 / 4 | 2.4 | Yes |
66814 | ![]() | C28H30N6O6S2 | 610.704 | 9 / 5 | 5.4 | No |
67128 | ![]() | C32H38N4O5S | 590.739 | 8 / 4 | 4.3 | No |
68365 | ![]() | C37H36FN5O7 | 681.721 | 9 / 6 | 5.0 | No |
69209 | ![]() | C34H37FN2O6 | 588.676 | 7 / 1 | 5.2 | No |
69930 | ![]() | C34H41N3O5 | 571.718 | 5 / 2 | 6.0 | No |
70601 | ![]() | C32H37N3O3 | 511.666 | 4 / 3 | 7.1 | No |
71123 | ![]() | C41H45N5O7 | 719.839 | 7 / 6 | 5.8 | No |
73122 | ![]() | C36H40N10O4S2 | 740.902 | 9 / 6 | 2.3 | No |
73335 | ![]() | C46H49N3O5 | 723.914 | 5 / 5 | 5.8 | No |
74483 | ![]() | C24H22N6O6S2 | 554.596 | 9 / 6 | 4.4 | No |
76697 | ![]() | C46H37N3O7 | 743.816 | 7 / 5 | 6.5 | No |
77366 | ![]() | C34H41N3O4 | 555.719 | 4 / 3 | 5.6 | No |
78102 | ![]() | C45H56N6O12 | 872.973 | 14 / 11 | N/A | No |
80796 | ![]() | C30H32FN3O3 | 501.602 | 5 / 3 | 7.0 | No |
81475 | ![]() | C27H24BrN3O2 | 502.412 | 3 / 1 | 5.9 | No |
82223 | ![]() | C26H26N4O6 | 490.516 | 6 / 3 | 2.6 | Yes |
82313 | ![]() | C21H24N6O6S2 | 520.579 | 9 / 6 | 3.1 | No |
83342 | ![]() | C43H49N7O5 | 743.909 | 7 / 4 | 4.6 | No |
83422 | ![]() | C29H34N2O3 | 458.602 | 3 / 2 | 5.5 | No |
83530 | ![]() | C30H34N4O6 | 546.624 | 6 / 4 | 3.2 | No |
83531 | ![]() | C30H34N4O6 | 546.624 | 6 / 4 | 3.2 | No |
86230 | ![]() | C29H35N5O3 | 501.631 | 5 / 2 | 4.7 | No |
87605 | ![]() | C44H50N6O8 | 790.918 | 8 / 6 | 5.4 | No |
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