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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL236630
Molecular formula	C25H30ClN3O
IUPAC name	N-(4-aminobutyl)-N-[(Z)-2-chloro-3-phenylprop-2-enyl]-4-(1H-indol-3-yl)butanamide
Molecular weight	423.985
Hydrogen bond acceptor	2
Hydrogen bond donor	2
XlogP	4.6
Synonyms	BDBM50217632 (Z)-N-(4-aminobutyl)-N-(2-chloro-3-phenylallyl)-4-(1H-indol-3-yl)butanamide
Inchi Key	DFLHMQJGWDDBDL-XLNRJJMWSA-N
Inchi ID	InChI=1S/C25H30ClN3O/c26-22(17-20-9-2-1-3-10-20)19-29(16-7-6-15-27)25(30)14-8-11-21-18-28-24-13-5-4-12-23(21)24/h1-5,9-10,12-13,17-18,28H,6-8,11,14-16,19,27H2/b22-17-
PubChem CID	44434633
ChEMBL	CHEMBL236630
IUPHAR	N/A
BindingDB	50217632
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
58655	Melanocortin receptor 3	P41968	MC3R	Homo sapiens (Human)	323
58653	Melanocortin receptor 4	P32245	MC4R	Homo sapiens (Human)	332
58654	Melanocortin receptor 5	P33032	MC5R	Homo sapiens (Human)	325
58656	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315

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