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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL385133
Molecular formula	C25H29FN2O4
IUPAC name	2-[2-[4-[6-fluoro-1-(2-methoxyethyl)indol-3-yl]piperidin-1-yl]ethoxy]benzoic acid
Molecular weight	440.515
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	1.4
Synonyms	2-(2-{4-[6-fluoro-1-(2-methoxyethyl)-1H-indol-3-yl]piperidin-1-yl}ethoxy)benzoic acid BDBM50156863
Inchi Key	DDRDBIHCGXAAID-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H29FN2O4/c1-31-14-13-28-17-22(20-7-6-19(26)16-23(20)28)18-8-10-27(11-9-18)12-15-32-24-5-3-2-4-21(24)25(29)30/h2-7,16-18H,8-15H2,1H3,(H,29,30)
PubChem CID	11362693
ChEMBL	CHEMBL385133
IUPHAR	N/A
BindingDB	50156863
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
57374	Histamine H1 receptor	P70174	Hrh1	Mus musculus (Mouse)	488
57375	Histamine H1 receptor	P31389	HRH1	Cavia porcellus (Guinea pig)	488
57376	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359

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