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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(6E)-5-imino-2-isobutyl-6-[(4-oxo-4H-chromen-3-yl)methylene]-5,6-dihydro-7H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one
Molecular formula	C19H16N4O3S
IUPAC name	(6E)-5-imino-2-(2-methylpropyl)-6-[(4-oxochromen-3-yl)methylidene]-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-one
Molecular weight	380.422
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.1
Synonyms	HMS2603H12 SMR000309728 ZINC5035166 MLS000731453 SR-01000133607 CHEMBL1393008 MolPort-007-655-390 SR-01000133607-1 AKOS001842169 [ Show all ]
Inchi Key	DCGYCKQJUCASPU-NYQGWRSHSA-N
Inchi ID	InChI=1S/C19H16N4O3S/c1-10(2)7-15-22-23-17(20)13(18(25)21-19(23)27-15)8-11-9-26-14-6-4-3-5-12(14)16(11)24/h3-6,8-10,20H,7H2,1-2H3/b13-8+,20-17?
PubChem CID	16193840
ChEMBL	CHEMBL1393008
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
469892	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
56351	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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