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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL109472
Molecular formula	C31H28N2O2
IUPAC name	N-[(3R)-1-benzylpyrrolidin-3-yl]-1-methoxy-4-(2-phenylethynyl)naphthalene-2-carboxamide
Molecular weight	460.577
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.2
Synonyms	BDBM50132697 N-[(3R)-1-Benzyl-3alpha-pyrrolidinyl]-1-methoxy-4-(phenylethynyl)naphthalene-2-carboxamide 1-Methoxy-4-phenylethynyl-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide
Inchi Key	DAUORZLLBDGUDH-AREMUKBSSA-N
Inchi ID	InChI=1S/C31H28N2O2/c1-35-30-28-15-9-8-14-27(28)25(17-16-23-10-4-2-5-11-23)20-29(30)31(34)32-26-18-19-33(22-26)21-24-12-6-3-7-13-24/h2-15,20,26H,18-19,21-22H2,1H3,(H,32,34)/t26-/m1/s1
PubChem CID	44340415
ChEMBL	CHEMBL109472
IUPHAR	N/A
BindingDB	50132697
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
55358	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
55356	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
55359	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
55357	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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