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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	Q95136
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2967
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL109472
Molecular formula	C31H28N2O2
IUPAC name	N-[(3R)-1-benzylpyrrolidin-3-yl]-1-methoxy-4-(2-phenylethynyl)naphthalene-2-carboxamide
Molecular weight	460.577
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.2
Synonyms	BDBM50132697 N-[(3R)-1-Benzyl-3alpha-pyrrolidinyl]-1-methoxy-4-(phenylethynyl)naphthalene-2-carboxamide 1-Methoxy-4-phenylethynyl-naphthalene-2-carboxylic acid ((R)-1-benzyl-pyrrolidin-3-yl)-amide
Inchi Key	DAUORZLLBDGUDH-AREMUKBSSA-N
Inchi ID	InChI=1S/C31H28N2O2/c1-35-30-28-15-9-8-14-27(28)25(17-16-23-10-4-2-5-11-23)20-29(30)31(34)32-26-18-19-33(22-26)21-24-12-6-3-7-13-24/h2-15,20,26H,18-19,21-22H2,1H3,(H,32,34)/t26-/m1/s1
PubChem CID	44340415
ChEMBL	CHEMBL109472
IUPHAR	N/A
BindingDB	50132697
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
Ki	2800.0 nM	PMID12951112	BindingDB,ChEMBL
Ki	3300.0 nM	PMID12951112	BindingDB,ChEMBL

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