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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL272439
Molecular formula	C20H22ClN5O2
IUPAC name	2-[3-(1-benzyl-8-chloro-2,5-dioxo-3,4-dihydro-1,4-benzodiazepin-3-yl)propyl]guanidine
Molecular weight	399.879
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	1.7
Synonyms	BDBM50374124
Inchi Key	CWVXKDNUHVPLLR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22ClN5O2/c21-14-8-9-15-17(11-14)26(12-13-5-2-1-3-6-13)19(28)16(25-18(15)27)7-4-10-24-20(22)23/h1-3,5-6,8-9,11,16H,4,7,10,12H2,(H,25,27)(H4,22,23,24)
PubChem CID	44457021
ChEMBL	CHEMBL272439
IUPHAR	N/A
BindingDB	50374124
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52481	Melanocortin receptor 3	P33033	Mc3r	Mus musculus (Mouse)	323
52480	Melanocortin receptor 4	P56450	Mc4r	Mus musculus (Mouse)	332
52479	Melanocortin receptor 5	P41149	Mc5r	Mus musculus (Mouse)	325
52482	Melanocyte-stimulating hormone receptor	Q01727	Mc1r	Mus musculus (Mouse)	315

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