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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL217254
Molecular formula	C23H28N4O
IUPAC name	[4-[4-[(3R)-3,4-dimethylpiperazin-1-yl]anilino]-3-methylquinolin-2-yl]methanol
Molecular weight	376.504
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	3.6
Synonyms	BDBM50196126 (R)-{4-[4-(3,4-dimethylpiperazin-1-yl)phenylamino]-3-methylquinolin-2-yl}methanol
Inchi Key	CWSVSBNTQJZFGE-MRXNPFEDSA-N
Inchi ID	InChI=1S/C23H28N4O/c1-16-14-27(13-12-26(16)3)19-10-8-18(9-11-19)24-23-17(2)22(15-28)25-21-7-5-4-6-20(21)23/h4-11,16,28H,12-15H2,1-3H3,(H,24,25)/t16-/m1/s1
PubChem CID	16090601
ChEMBL	CHEMBL217254
IUPHAR	N/A
BindingDB	50196126
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
52409	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
52407	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
52408	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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