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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS001199098
Molecular formula	C25H35N5O
IUPAC name	N-[2-(diethylamino)ethyl]-3-[3,4,6-trimethyl-1-(4-methylphenyl)pyrazolo[3,4-b]pyridin-5-yl]propanamide
Molecular weight	421.589
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	4.3
Synonyms	N-[2-(diethylamino)ethyl]-3-[3,4,6-trimethyl-1-(4-methylphenyl)pyrazolo[3,4-b]pyridin-5-yl]propanamide CHEMBL1319565 MCULE-5790689067 ZINC5151977 N-[2-(diethylamino)ethyl]-3-[3,4,6-trimethyl-1-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridin-5-yl]propanamide BDBM62138 N-[2-(diethylamino)ethyl]-3-[3,4,6-trimethyl-1-(p-tolyl)pyrazolo[3,4-b]pyridin-5-yl]propionamide cid_23603500 N-[2-(diethylamino)ethyl]-3-[3,4,6-trimethyl-1-(4-methylphenyl)-5-pyrazolo[3,4-b]pyridinyl]propanamide SMR000563225 HMS2868O15 MolPort-007-684-590 AKOS001865324 [ Show all ]
Inchi Key	CRZGIBBJIJHGEQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H35N5O/c1-7-29(8-2)16-15-26-23(31)14-13-22-18(4)24-20(6)28-30(25(24)27-19(22)5)21-11-9-17(3)10-12-21/h9-12H,7-8,13-16H2,1-6H3,(H,26,31)
PubChem CID	23603500
ChEMBL	CHEMBL1319565
IUPHAR	N/A
BindingDB	62138
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
49269	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
49268	Melanin-concentrating hormone receptor 1	Q99705	MCHR1	Homo sapiens (Human)	422
49270	Neuropeptides B/W receptor type 1	P48145	NPBWR1	Homo sapiens (Human)	328
468955	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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