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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL384925
Molecular formula	C28H30N4
IUPAC name	3-benzyl-2-methyl-N-[4-(4-methylpiperazin-1-yl)phenyl]quinolin-4-amine
Molecular weight	422.576
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	6.0
Synonyms	BDBM50196128 (3-benzyl-2-methylquinolin-4-yl)-[4-(4-methylpiperazin-1-yl)-phenyl]amine
Inchi Key	CNOXIXMPZLKURQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H30N4/c1-21-26(20-22-8-4-3-5-9-22)28(25-10-6-7-11-27(25)29-21)30-23-12-14-24(15-13-23)32-18-16-31(2)17-19-32/h3-15H,16-20H2,1-2H3,(H,29,30)
PubChem CID	16090621
ChEMBL	CHEMBL384925
IUPHAR	N/A
BindingDB	50196128
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
46216	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
46217	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
46218	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462

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