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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2112223
Molecular formula	C30H37N5O2
IUPAC name	N-[(2R)-1-(5-aminopentylamino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl]spiro[indene-1,4'-piperidine]-1'-carboxamide
Molecular weight	499.659
Hydrogen bond acceptor	3
Hydrogen bond donor	4
XlogP	3.9
Synonyms	BDBM50454937 (R)-N-(5-Aminopentyl)-2-[[spiro[piperidine-4,1'-[1H]indene]-1-yl]carbonylamino]-3-(1H-indole-3-yl)propanamide
Inchi Key	CIZDAUBRPMKZKS-HHHXNRCGSA-N
Inchi ID	InChI=1S/C30H37N5O2/c31-16-6-1-7-17-32-28(36)27(20-23-21-33-26-11-5-3-9-24(23)26)34-29(37)35-18-14-30(15-19-35)13-12-22-8-2-4-10-25(22)30/h2-5,8-13,21,27,33H,1,6-7,14-20,31H2,(H,32,36)(H,34,37)/t27-/m1/s1
PubChem CID	9827283
ChEMBL	CHEMBL2112223
IUPHAR	N/A
BindingDB	50454937
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
43094	Somatostatin receptor type 1	P30872	SSTR1	Homo sapiens (Human)	391
43097	Somatostatin receptor type 2	P30874	SSTR2	Homo sapiens (Human)	369
43098	Somatostatin receptor type 3	P32745	SSTR3	Homo sapiens (Human)	418
43096	Somatostatin receptor type 4	P31391	SSTR4	Homo sapiens (Human)	388
43095	Somatostatin receptor type 5	P35346	SSTR5	Homo sapiens (Human)	364

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