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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL267853
Molecular formula	C17H18ClN5
IUPAC name	3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyrimidine
Molecular weight	327.816
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	1-(4-chlorophenyl)-4-({imidazo[1,2-a]pyrimidin-3-yl}methyl)piperazine MCULE-8669888631 ZINC25973011 221470-64-0 MolPort-028-783-866 AKOS033429972 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-imidazo[1,2-a]pyrimidine Z1562961320 BDBM50073808 [ Show all ]
Inchi Key	CFXIWIZPWMZACA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18ClN5/c18-14-2-4-15(5-3-14)22-10-8-21(9-11-22)13-16-12-20-17-19-6-1-7-23(16)17/h1-7,12H,8-11,13H2
PubChem CID	44264622
ChEMBL	CHEMBL267853
IUPHAR	N/A
BindingDB	50073808
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
41059	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
41057	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444
41060	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
41058	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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