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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	Q95136
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2967
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL267853
Molecular formula	C17H18ClN5
IUPAC name	3-[[4-(4-chlorophenyl)piperazin-1-yl]methyl]imidazo[1,2-a]pyrimidine
Molecular weight	327.816
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	3.2
Synonyms	ZINC25973011 221470-64-0 MolPort-028-783-866 AKOS033429972 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-imidazo[1,2-a]pyrimidine Z1562961320 BDBM50073808 1-(4-chlorophenyl)-4-({imidazo[1,2-a]pyrimidin-3-yl}methyl)piperazine MCULE-8669888631 [ Show all ]
Inchi Key	CFXIWIZPWMZACA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H18ClN5/c18-14-2-4-15(5-3-14)22-10-8-21(9-11-22)13-16-12-20-17-19-6-1-7-23(16)17/h1-7,12H,8-11,13H2
PubChem CID	44264622
ChEMBL	CHEMBL267853
IUPHAR	N/A
BindingDB	50073808
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	21000.0 nM	PMID9990464	BindingDB,ChEMBL

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