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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	ethopropazine
Molecular formula	C19H24N2S
IUPAC name	N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine
Molecular weight	312.475
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.8
Synonyms	Isothiazine L001334 N,N-diethyl-1-(10H-phenothiazin-10-yl)propan-2-amine Pardidol 10-(2-(Diethylamino)propyl)-phenothiazin Parsidan (TN) 10H-Phenothiazine-10-ethanamine, N,N-diethyl-alpha-methyl- Phenothiazine, 10-[2-(diethylamino)propyl]- Athapropazine Profenamina CHEBI:313639 Prophenamine diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine SCHEMBL34045 Fempropazine Spectrum_000815 W 483 KBio2_003863 Lysivane (Salt/Mix) N,N-Diethyl-alpha-methyl-10H-phenothiazine-10-ethanamine Parkin 10-[2-(Diethylamino)-1-Propyl]phenothiazine Parsitan Prestwick2_000840 BPBio1_000879 Profenamine D0Q0RC Rocipel EINECS 208-320-4 SPBio_002720 GTPL7181 Isotazin KBioGR_001215 N,N-Diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine NINDS_000061 Parphezein (Salt/Mix) 10-[2-DIETHYLAMINOPROPYL]PHENOTHIAZINE Phenoprozine AC1L1FLK Prodictazin (Salt/Mix) BSPBio_002018 Profenaminum DB00392 SBI-0051378.P003 Spectrum4_000548 KBio1_000061 LS-105451 N,N-diethyl-1-phe-nothiazin-10-yl-propan-2-amine Pardisol (Salt/Mix) 10-(2-DIETHYLAMINOPROPYL)-PHENOTHIAZINE Parsidol 2-Diethylamino-1-propyl-N-dibenzoparathiazine Prestwick0_000840 Athopropazin Profenamina [INN-Spanish] CHEMBL1206 Prophenaminum DivK1c_000061 SKF 2538 Fenpropazina SR-05000001626 W-483 KBio2_006431 MCULE-1873220615 NCGC00178860-03 Parkin (TN) 10-[2-(Diethylamino)-2-methylethyl]phenothiazine Parsotil AB00053474 Prestwick3_000840 BRD-A16311756-003-01-0 Profenamine (INN) DB-040867 Rodipal Ethapropazine Spectrum2_000984 IDI1_000061 Isothazine KBioSS_001295 N,N-Diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine # Parcidol (.+/-.)-Profenamine Parsidan 10H-Phenothiazine-10-ethanamine, N,N-diethyl-.alpha.-methyl- PHENOTHIAZINE, 10-(2-(DIETHYLAMINO)PROPYL)- Aethopropropazin Prodierazine CDOZDBSBBXSXLB-UHFFFAOYSA-N Profenaminum [INN-Latin] Dibutil (Salt/Mix) SC 2538 Etopropezina Spectrum5_001592 SR-05000001626-4 KBio2_001295 Lysivane N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine Parfezine 10-(2-Diethylaminopropyl)phenothiazine Parsidol(TN) 522-00-9 Prestwick1_000840 BDBM8958 Profenamina [Italian] D08426 Rochipel DTXSID2023018 SPBio_001047 FT-0697105 KBio3_001238 N,N-Diethyl-.alpha.-methyl-10H-phenothiazine-10-ethanamine NCIOpen2_008174 Parkisol 10-[2-(Diethylamino)propyl]phenothiazine Phenopropazine AB00053474_04 Prodictazin BSPBio_000799 Profenamine [INN:BAN] RP 3356 Ethopromazine Spectrum3_000429 Isopthazine [ Show all ]
Inchi Key	CDOZDBSBBXSXLB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3
PubChem CID	3290
ChEMBL	N/A
IUPHAR	7181
BindingDB	N/A
DrugBank	DB00392
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
39493	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
553443	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
39491	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
553442	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466

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