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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000714665
Molecular formula	C17H19NO4S2
IUPAC name	(5E)-5-[(3-ethoxy-4-hydroxyphenyl)methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one
Molecular weight	365.462
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	3.4
Synonyms	SMR000274644 AC1NXS8C HMS2699B15 (5E)-5-[(3-ethoxy-4-hydroxyphenyl)methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one SR-01000317233 BAS 00634568 CHEMBL1304807 (5E)-5-(3-ethoxy-4-hydroxy-benzylidene)-3-(tetrahydrofurfuryl)-2-thioxo-thiazolidin-4-one (5E)-5-[(3-ethoxy-4-oxidanyl-phenyl)methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one SR-01000317233-1 BDBM72494 cid_5758848 (5E)-5-[(3-ethoxy-4-hydroxyphenyl)methylidene]-3-(2-oxolanylmethyl)-2-sulfanylidene-4-thiazolidinone [ Show all ]
Inchi Key	CBGQEKXIRAJAAT-OQLLNIDSSA-N
Inchi ID	InChI=1S/C17H19NO4S2/c1-2-21-14-8-11(5-6-13(14)19)9-15-16(20)18(17(23)24-15)10-12-4-3-7-22-12/h5-6,8-9,12,19H,2-4,7,10H2,1H3/b15-9+
PubChem CID	5758848
ChEMBL	CHEMBL1304807
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
467600	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
37855	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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