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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL10147835
Molecular formula	C26H22ClF2N7O5
IUPAC name	N-[3-[[(1R)-1-[5-[5-chloro-3-fluoro-2-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl]-3-fluoropyridin-2-yl]ethyl]carbamoyl]oxetan-3-yl]-2-methoxypyrimidine-5-carboxamide
Molecular weight	585.953
Hydrogen bond acceptor	12
Hydrogen bond donor	2
XlogP	2.2
Synonyms	US8912221, 15 BDBM140542
Inchi Key	CAOFUTXBTGKTNT-GFCCVEGCSA-N
Inchi ID	InChI=1S/C26H22ClF2N7O5/c1-12(33-24(38)26(10-40-11-26)35-23(37)15-8-31-25(39-3)32-9-15)21-19(29)4-14(7-30-21)17-5-16(27)6-18(28)20(17)22-34-13(2)41-36-22/h4-9,12H,10-11H2,1-3H3,(H,33,38)(H,35,37)/t12-/m1/s1
PubChem CID	57382839
ChEMBL	N/A
IUPHAR	N/A
BindingDB	140542
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
558415	B1 bradykinin receptor	P46663	BDKRB1	Homo sapiens (Human)	353

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