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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL303678
Molecular formula	C20H21N5O3
IUPAC name	11-[2-(4-acetylpiperazin-1-yl)acetyl]-5H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Molecular weight	379.42
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	-0.4
Synonyms	11-[2-(4-Acetyl-piperazin-1-yl)-acetyl]-5,11-dihydro-benzo[e]pyrido[3,2-b][1,4]diazepin-6-one BDBM50012354 5,11-Dihydro-11-[[4-acetyl-1-piperazinyl]acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Inchi Key	BRGCUQPQKZURGP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H21N5O3/c1-14(26)24-11-9-23(10-12-24)13-18(27)25-17-7-3-2-5-15(17)20(28)22-16-6-4-8-21-19(16)25/h2-8H,9-13H2,1H3,(H,22,28)
PubChem CID	15050937
ChEMBL	CHEMBL303678
IUPHAR	N/A
BindingDB	50012354
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
30960	Muscarinic acetylcholine receptor M1	P08482	Chrm1	Rattus norvegicus (Rat)	460
30961	Muscarinic acetylcholine receptor M2	P10980	Chrm2	Rattus norvegicus (Rat)	466
30959	Muscarinic acetylcholine receptor M3	P08483	Chrm3	Rattus norvegicus (Rat)	589
30958	Muscarinic acetylcholine receptor M4	P08485	Chrm4	Rattus norvegicus (Rat)	478

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