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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL561123
Molecular formula	C22H28N6O2
IUPAC name	3-methyl-2-morpholin-4-yl-7-[(4-phenylpiperazin-1-yl)methyl]-5H-pyrrolo[3,2-d]pyrimidin-4-one
Molecular weight	408.506
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.1
Synonyms	BDBM50295929 3-Methyl-2-morpholin-4-yl-7-[(4-phenylpiperazin-1-yl)methyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Inchi Key	BPXOVNRRDFBZBM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28N6O2/c1-25-21(29)20-19(24-22(25)28-11-13-30-14-12-28)17(15-23-20)16-26-7-9-27(10-8-26)18-5-3-2-4-6-18/h2-6,15,23H,7-14,16H2,1H3
PubChem CID	45268293
ChEMBL	CHEMBL561123
IUPHAR	N/A
BindingDB	50295929
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
29989	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
29987	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
29988	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
522451	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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