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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	D(1A) dopamine receptor
Species	Bos taurus (Bovine)
Gene	DRD1
Synonym	Dopamine D1 receptor
Disease	N/A for non-human GPCRs
Length	446
Amino acid sequence	MRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProt	Q95136
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL2967
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL561123
Molecular formula	C22H28N6O2
IUPAC name	3-methyl-2-morpholin-4-yl-7-[(4-phenylpiperazin-1-yl)methyl]-5H-pyrrolo[3,2-d]pyrimidin-4-one
Molecular weight	408.506
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	1.1
Synonyms	BDBM50295929 3-Methyl-2-morpholin-4-yl-7-[(4-phenylpiperazin-1-yl)methyl]-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one
Inchi Key	BPXOVNRRDFBZBM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H28N6O2/c1-25-21(29)20-19(24-22(25)28-11-13-30-14-12-28)17(15-23-20)16-26-7-9-27(10-8-26)18-5-3-2-4-6-18/h2-6,15,23H,7-14,16H2,1H3
PubChem CID	45268293
ChEMBL	CHEMBL561123
IUPHAR	N/A
BindingDB	50295929
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	520.0 nM	PMID19481941	BindingDB,ChEMBL

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