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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL200204
Molecular formula	C25H31N3O2
IUPAC name	8-[(1R,2R)-2-hydroxy-2-phenylcyclohexyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
Molecular weight	405.542
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	3.6
Synonyms	8-((cis, rac)-2-hydroxy-2-phenyl-cyclohexyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one BDBM50175955 SCHEMBL5556686
Inchi Key	BONFVDJOYDFOEN-RCZVLFRGSA-N
Inchi ID	InChI=1S/C25H31N3O2/c29-23-24(28(19-26-23)21-11-5-2-6-12-21)15-17-27(18-16-24)22-13-7-8-14-25(22,30)20-9-3-1-4-10-20/h1-6,9-12,22,30H,7-8,13-19H2,(H,26,29)/t22-,25-/m1/s1
PubChem CID	44406538
ChEMBL	CHEMBL200204
IUPHAR	N/A
BindingDB	50175955
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
28948	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
28947	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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