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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	[8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic Acid
Molecular formula	C30H33N3O3
IUPAC name	2-[8-(3,3-diphenylpropyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl]acetic acid
Molecular weight	483.612
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	2.9
Synonyms	L001685 BDBM86491 LS-192858 DiPOA SCHEMBL5092002
Inchi Key	BNMJRKJLCRSUJA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C30H33N3O3/c34-28(35)22-32-23-33(26-14-8-3-9-15-26)30(29(32)36)17-20-31(21-18-30)19-16-27(24-10-4-1-5-11-24)25-12-6-2-7-13-25/h1-15,27H,16-23H2,(H,34,35)
PubChem CID	9848149
ChEMBL	N/A
IUPHAR	N/A
BindingDB	86491
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
28253	Kappa-type opioid receptor	P41145	OPRK1	Homo sapiens (Human)	380
555592	Mu-type opioid receptor	P35372	OPRM1	Homo sapiens (Human)	400
459458	Nociceptin receptor	P41146	OPRL1	Homo sapiens (Human)	370

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