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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000581434
Molecular formula	C14H10ClF2N3O4
IUPAC name	1-[3-chloro-4-(difluoromethoxy)phenyl]-3-(4-nitrophenyl)urea
Molecular weight	357.698
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	4.1
Synonyms	N-[4-(difluoromethoxy)-3-chlorophenyl][(4-nitrophenyl)amino]carboxamide HMS2549M24 STK459577 1-[4-[bis(fluoranyl)methoxy]-3-chloranyl-phenyl]-3-(4-nitrophenyl)urea AKOS003328539 MolPort-001-627-132 CHEMBL1342907 SMR000200059 MCULE-4000651672 ZINC5042000 BDBM67975 N-[3-chloro-4-(difluoromethoxy)phenyl]-N'-(4-nitrophenyl)urea cid_2957586 ST50838258 1-[3-chloro-4-(difluoromethoxy)phenyl]-3-(4-nitrophenyl)urea AC1MG9FZ [ Show all ]
Inchi Key	BMQFHNRBXLDKPP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H10ClF2N3O4/c15-11-7-9(3-6-12(11)24-13(16)17)19-14(21)18-8-1-4-10(5-2-8)20(22)23/h1-7,13H,(H2,18,19,21)
PubChem CID	2957586
ChEMBL	CHEMBL1342907
IUPHAR	N/A
BindingDB	67975
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27688	C-C chemokine receptor type 6	P51684	CCR6	Homo sapiens (Human)	374
27689	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
27690	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
466303	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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