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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000559431
Molecular formula	C32H33N3O3
IUPAC name	2'-amino-6,7',7',9,11,11-hexamethyl-2,5'-dioxo-9-phenylspiro[1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-triene-3,4'-6,8-dihydrochromene]-3'-carbonitrile
Molecular weight	507.634
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.0
Synonyms	774561-48-7 cid_4886081 STK210677 AKOS002530396 2-amino-4',4',6',7,7,8'-hexamethyl-2',5-dioxo-6'-phenyl-5,5',6,6',7,8-hexahydro-4'{H}-spiro[chromene-4,1'-pyrrolo[3,2,1-{ij}]quinoline]-3-carbonitrile SMR000149547 AC1NKD4Y HMS2447N15 AKOS016309081 MLS002584805 CHEMBL1528880 ST50161499 AKOS002267501 MCULE-4788036663 2-amino-4',4',6',7,7,8'-hexamethyl-2',5-dioxo-6'-phenyl-5,5',6,6',7,8-hexahydro-4'H-spiro[chromene-4,1'-pyrrolo[3,2,1-ij]quinoline]-3-carbonitrile BDBM67858 MolPort-000-511-106 [ Show all ]
Inchi Key	BMPGAVJJJFFABI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H33N3O3/c1-18-12-20-26-21(13-18)32(22(16-33)27(34)38-24-15-29(2,3)14-23(36)25(24)32)28(37)35(26)30(4,5)17-31(20,6)19-10-8-7-9-11-19/h7-13H,14-15,17,34H2,1-6H3
PubChem CID	4886081
ChEMBL	CHEMBL1528880
IUPHAR	N/A
BindingDB	67858
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
27669	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
27670	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
27668	Neurotensin receptor type 1	P30989	NTSR1	Homo sapiens (Human)	418

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