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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	(R)-timolol
Molecular formula	C13H24N4O3S
IUPAC name	(2R)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
Molecular weight	316.42
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	1.8
Synonyms	Spectrum5_000582 (2R)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol 2BG20ZUO2E BRD-K30421593-050-02-3 DivK1c_000178 KBio3_002112 R)-Timolol SCHEMBL222970 TX-015671 AC1L5283 CHEBI:39466 IDI1_000178 L 714465 Spectrum3_001366 (+)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol 2-Propanol,1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-,(2R)- BDBM50404945 CTK4F8603 KBio2_003240 NINDS_000178 Spectrum_000192 (2r)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol BRD-K30421593-050-03-1 EINECS 248-033-1 KBioGR_001767 R-Timolol SPBio_001487 UNII-2BG20ZUO2E 1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-2-propanol AC1Q59G3 KBio1_000178 MCULE-6334087691 Spectrum4_001164 (+)-timolol 26839-76-9 BLJRIMJGRPQVNF-SNVBAGLBSA-N d-Timolol KBio2_005808 R)-(+)-Timolol SBI-0051535.P003 Timolol, (+)- (r)-1-(tert-butylamino)-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-ol AB00053554_02 BSPBio_002892 FT-0700860 KBioSS_000672 Spectrum2_001334 ZINC403609 2-Propanol, 1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)- AKOS030254981 CHEMBL1744069 KBio2_000672 NCGC00178405-01 [ Show all ]
Inchi Key	BLJRIMJGRPQVNF-SNVBAGLBSA-N
Inchi ID	InChI=1S/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,1-3H3/t10-/m1/s1
PubChem CID	168613
ChEMBL	CHEMBL1744069
IUPHAR	N/A
BindingDB	50404945
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
26705	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418

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