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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	UNII-NGJ1K8EOK1
Molecular formula	C21H26N4
IUPAC name	(6S)-2-phenyl-6-[(4-phenylpiperazin-1-yl)methyl]-1,4,5,6-tetrahydropyrimidine
Molecular weight	334.467
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.9
Synonyms	(4S)-2-Phenyl-4alpha-(4-phenylpiperazinomethyl)-1,4,5,6-tetrahydropyrimidine NGJ1K8EOK1 562104-72-7 (+)-(6S)-3,4,5,6-Tetrahydro-2-phenyl-6-((4-phenyl-1-piperazinyl)methyl)pyrimidine CHEMBL169459 (S)-2-Phenyl-4-(4-phenyl-piperazin-1-ylmethyl)-1,4,5,6-tetrahydro-pyrimidine Pyrimidine, 1,4,5,6-tetrahydro-2-phenyl-4-((4-phenyl-1-piperazinyl)methyl)-, (4S)- BDBM50124193 (+)-Fauc-312 FAUC-312 Pyrimidine, 3,4,5,6-tetrahydro-2-phenyl-4-((4-phenyl-1-piperazinyl)methyl)-, (4S)- [ Show all ]
Inchi Key	BJWYIHWMKMZYRS-IBGZPJMESA-N
Inchi ID	InChI=1S/C21H26N4/c1-3-7-18(8-4-1)21-22-12-11-19(23-21)17-24-13-15-25(16-14-24)20-9-5-2-6-10-20/h1-10,19H,11-17H2,(H,22,23)/t19-/m0/s1
PubChem CID	10359539
ChEMBL	CHEMBL169459
IUPHAR	N/A
BindingDB	50124193
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
25527	D(1A) dopamine receptor	Q95136	DRD1	Bos taurus (Bovine)	446
25528	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
25525	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
25526	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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