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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidine-2-carboxylic acid
Molecular formula	C12H9N3O3
IUPAC name	6-methyl-2-oxo-1,6,8-triazatricyclo[7.4.0.03,7]trideca-3(7),4,8,10,12-pentaene-5-carboxylic acid
Molecular weight	243.222
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	0.5
Synonyms	NE38960 6-methyl-2-oxo-1,6,8-triazatricyclo[7.4.0.0^{3,7}]trideca-3(7),4,8,10,12-pentaene-5-carboxylic acid EN300-12428 ZINC387246 AC1Q3XM6 MLS000760779 6-methyl-2-oxo-1,6,8-triazatricyclo[7.4.0.0(3),]trideca-3(7),4,8,10,12-pentaene-5-carboxylic acid CHEMBL1304220 SMR000370873 724738-59-4 HMS2765O20 AKOS008064301 MolPort-002-468-390 6-methyl-2-oxo-1,6,8-triazatricyclo[7.4.0.0?,?]trideca-3(7),4,8,10,12-pentaene-5-carboxylic acid CTK7H1689 Z220533958 AC1LGV16 MCULE-1234451132 [ Show all ]
Inchi Key	BHMLNQBJJMJWKY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H9N3O3/c1-14-8(12(17)18)6-7-10(14)13-9-4-2-3-5-15(9)11(7)16/h2-6H,1H3,(H,17,18)
PubChem CID	852288
ChEMBL	CHEMBL1304220
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
465858	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593
23882	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
23880	Relaxin receptor 2	Q8WXD0	RXFP2	Homo sapiens (Human)	754
23881	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424

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