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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL364246
Molecular formula	C28H31N5O4S
IUPAC name	1-tert-butyl-3-[2-[(2-methoxy-5-nitrophenyl)methylsulfanyl]-1-(2-phenylethyl)benzimidazol-5-yl]urea
Molecular weight	533.647
Hydrogen bond acceptor	6
Hydrogen bond donor	2
XlogP	5.5
Synonyms	BDBM50165527 1-tert-Butyl-3-[2-(2-methoxy-5-nitro-benzylsulfanyl)-1-phenethyl-1H-benzoimidazol-5-yl]-urea
Inchi Key	BGUUISPXZIOHRA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H31N5O4S/c1-28(2,3)31-26(34)29-21-10-12-24-23(17-21)30-27(32(24)15-14-19-8-6-5-7-9-19)38-18-20-16-22(33(35)36)11-13-25(20)37-4/h5-13,16-17H,14-15,18H2,1-4H3,(H2,29,31,34)
PubChem CID	44402105
ChEMBL	CHEMBL364246
IUPHAR	N/A
BindingDB	50165527
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
23442	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327
23443	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328

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