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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3617616
Molecular formula	C19H16ClFN4O2
IUPAC name	(7R)-5-(4-chlorophenyl)-2-[(5-fluoropyridin-2-yl)oxymethyl]-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazin-4-one
Molecular weight	386.811
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.2
Synonyms	BDBM50122276 (7R)-2-(5-Fluoro-2-pyridyloxy)methyl-5-(4-chlorophenyl)-7-methyl-6,7-dihydropyrazolo[1,5-a]pyrazine-4(5H)-one
Inchi Key	BGUIRBNHGKTOPB-GFCCVEGCSA-N
Inchi ID	InChI=1S/C19H16ClFN4O2/c1-12-10-24(16-5-2-13(20)3-6-16)19(26)17-8-15(23-25(12)17)11-27-18-7-4-14(21)9-22-18/h2-9,12H,10-11H2,1H3/t12-/m1/s1
PubChem CID	122190393
ChEMBL	CHEMBL3617616
IUPHAR	N/A
BindingDB	50122276
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
465786	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
465787	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203

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