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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL102429
Molecular formula	C16H15N3O
IUPAC name	7-(dimethylamino)-2-phenyl-1H-1,8-naphthyridin-4-one
Molecular weight	265.316
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.9
Synonyms	ZINC13579545 7-Dimethylamino-2-phenyl-[1,8]naphthyridin-4-ol BDBM50147858 D06QRI 7-(dimethylamino)-2-phenyl-1,8-naphthyridin-4-ol
Inchi Key	BEMRWFAUJDRLIY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H15N3O/c1-19(2)15-9-8-12-14(20)10-13(17-16(12)18-15)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,20)
PubChem CID	10378184
ChEMBL	CHEMBL102429
IUPHAR	N/A
BindingDB	50147858
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21716	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
21717	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
21715	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412

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