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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Adenosine receptor A1
Species	Bos taurus (Bovine)
Gene	ADORA1
Synonym	N/A
Disease	N/A for non-human GPCRs
Length	326
Amino acid sequence	MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPRTYFHTCLKVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTPRRAVVAITGCWILSFVVGLTPMFGWNNLSAVERDWLANGSVGEPVIECQFEKVISMEYMVYFNFFVWVLPPLLLMVLIYMEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPSCHMPRILIYIAIFLSHGNSAMNPIVYAFRIQKFRVTFLKIWNDHFRCQPAPPVDEDAPAERPDD
UniProt	P28190
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4975
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL102429
Molecular formula	C16H15N3O
IUPAC name	7-(dimethylamino)-2-phenyl-1H-1,8-naphthyridin-4-one
Molecular weight	265.316
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.9
Synonyms	ZINC13579545 7-Dimethylamino-2-phenyl-[1,8]naphthyridin-4-ol BDBM50147858 D06QRI 7-(dimethylamino)-2-phenyl-1,8-naphthyridin-4-ol
Inchi Key	BEMRWFAUJDRLIY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H15N3O/c1-19(2)15-9-8-12-14(20)10-13(17-16(12)18-15)11-6-4-3-5-7-11/h3-10H,1-2H3,(H,17,18,20)
PubChem CID	10378184
ChEMBL	CHEMBL102429
IUPHAR	N/A
BindingDB	50147858
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Ki	0.56 nM	PMID15163184	BindingDB,ChEMBL
Ki	6.02 nM	PMID15163184	BindingDB,ChEMBL

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