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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL136468
Molecular formula	C22H26ClFN2
IUPAC name	4-[6-chloro-3-(2-fluorophenyl)-2,3-dihydro-1H-inden-1-yl]-1,2,2-trimethylpiperazine
Molecular weight	372.912
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	4.8
Synonyms	BDBM50029405 SCHEMBL8107803 4-[6-Chloro-3-(2-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine
Inchi Key	BEJFETGIBLFMPS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26ClFN2/c1-22(2)14-26(11-10-25(22)3)21-13-18(17-6-4-5-7-20(17)24)16-9-8-15(23)12-19(16)21/h4-9,12,18,21H,10-11,13-14H2,1-3H3
PubChem CID	10809335
ChEMBL	CHEMBL136468
IUPHAR	N/A
BindingDB	50029405
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21593	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
21595	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
21594	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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