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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL137536
Molecular formula	C22H26F2N2
IUPAC name	4-[7-fluoro-3-(4-fluorophenyl)-2,3-dihydro-1H-inden-1-yl]-1,2,2-trimethylpiperazine
Molecular weight	356.461
Hydrogen bond acceptor	4
Hydrogen bond donor	0
XlogP	4.3
Synonyms	BDBM50029368 SCHEMBL8117005 4-[7-Fluoro-3-(4-fluoro-phenyl)-indan-1-yl]-1,2,2-trimethyl-piperazine
Inchi Key	BEBKQEVGPRNSGI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H26F2N2/c1-22(2)14-26(12-11-25(22)3)20-13-18(15-7-9-16(23)10-8-15)17-5-4-6-19(24)21(17)20/h4-10,18,20H,11-14H2,1-3H3
PubChem CID	10570260
ChEMBL	CHEMBL137536
IUPHAR	N/A
BindingDB	50029368
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21417	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
21416	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
21415	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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