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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL350853
Molecular formula	C23H27N5O2
IUPAC name	1-(1-methyl-2-oxo-5-piperidin-1-yl-3H-1,4-benzodiazepin-3-yl)-3-(3-methylphenyl)urea
Molecular weight	405.502
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	2.7
Synonyms	BDBM50040672 L008783 1-(1-Methyl-2-oxo-5-piperidin-1-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)-3-m-tolyl-urea
Inchi Key	BDZOCUCJHUMDAN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H27N5O2/c1-16-9-8-10-17(15-16)24-23(30)26-20-22(29)27(2)19-12-5-4-11-18(19)21(25-20)28-13-6-3-7-14-28/h4-5,8-12,15,20H,3,6-7,13-14H2,1-2H3,(H2,24,26,30)
PubChem CID	10341247
ChEMBL	CHEMBL350853
IUPHAR	N/A
BindingDB	50040672
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
21369	Cholecystokinin receptor type A	P30551	Cckar	Rattus norvegicus (Rat)	444
21370	Gastrin/cholecystokinin type B receptor	P32239	CCKBR	Homo sapiens (Human)	447

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