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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL62247
Molecular formula	C24H26N2O4
IUPAC name	ethyl 17-ethoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Molecular weight	406.482
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	9-Ethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester BDBM50071186
Inchi Key	BDIZCMDNZUBLMP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26N2O4/c1-4-28-16-6-7-17-15(12-16)10-11-26-13-18-20(30-23(17)26)9-8-19-22(18)21(14(3)25-19)24(27)29-5-2/h6-9,12,23,25H,4-5,10-11,13H2,1-3H3
PubChem CID	44302775
ChEMBL	CHEMBL62247
IUPHAR	N/A
BindingDB	50071186
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
20976	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
20973	Muscarinic acetylcholine receptor M2	P08172	CHRM2	Homo sapiens (Human)	466
20972	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
20975	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
20974	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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