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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL116246
Molecular formula	C27H33N3O2
IUPAC name	N-[(5-methylpyrazin-2-yl)methyl]-5-[(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)methyl]furan-2-carboxamide
Molecular weight	431.58
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	5.8
Synonyms	BDBM50121100 L019638 5-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-ylmethyl)-furan-2-carboxylic acid (5-methyl-pyrazin-2-ylmethyl)-amide
Inchi Key	AXWVIWLWIYHXAX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C27H33N3O2/c1-17-11-22-23(27(5,6)10-9-26(22,3)4)13-19(17)12-21-7-8-24(32-21)25(31)30-16-20-15-28-18(2)14-29-20/h7-8,11,13-15H,9-10,12,16H2,1-6H3,(H,30,31)
PubChem CID	9910626
ChEMBL	CHEMBL116246
IUPHAR	N/A
BindingDB	50121100
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
17182	Gonadotropin-releasing hormone receptor	P30968	GNRHR	Homo sapiens (Human)	328
17183	Gonadotropin-releasing hormone receptor	P30969	Gnrhr	Rattus norvegicus (Rat)	327

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