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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SCHEMBL5351769
Molecular formula	C26H24N6O5
IUPAC name	(2S)-2-[(6S)-1-(carboxymethyl)-6-phenyl-4,5-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-6-yl]-2-(4,6-dimethylpyrimidin-2-yl)oxyacetic acid
Molecular weight	500.515
Hydrogen bond acceptor	10
Hydrogen bond donor	3
XlogP	-0.5
Synonyms	(+/-)-(S)-((6S)-1-carboxymethyl-6-phenyl-5,6-dihydro-4H-2,3,5,10b-tetraaza-benzo[e]azulen-6-yl)-(4,6-dimethyl-pyrimidin-2-yloxy)-acetic acid CHEMBL2112377 AVUMTAXWDOUGCR-BVAGGSTKSA-N
Inchi Key	AVUMTAXWDOUGCR-BVAGGSTKSA-N
Inchi ID	InChI=1S/C26H24N6O5/c1-15-12-16(2)29-25(28-15)37-23(24(35)36)26(17-8-4-3-5-9-17)18-10-6-7-11-19(18)32-20(13-22(33)34)30-31-21(32)14-27-26/h3-12,23,27H,13-14H2,1-2H3,(H,33,34)(H,35,36)/t23-,26+/m1/s1
PubChem CID	11156301
ChEMBL	CHEMBL2112377
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
15656	Endothelin receptor type B	P24530	EDNRB	Homo sapiens (Human)	442
15657	Endothelin-1 receptor	P25101	EDNRA	Homo sapiens (Human)	427

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