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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL213201
Molecular formula	C26H23ClN6O
IUPAC name	N-[8-chloro-6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzodiazepin-11-yl]-4-cyanobenzamide
Molecular weight	470.961
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.1
Synonyms	BDBM50190074 N-[2-chloro-11-(4-methyl-piperazin-1-yl)-dibenzo[b,e][1,4]diazepin-5-yl]-4-cyano-benzamide
Inchi Key	AUKPHAAWNDZREH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H23ClN6O/c1-31-12-14-32(15-13-31)25-21-16-20(27)10-11-23(21)33(24-5-3-2-4-22(24)29-25)30-26(34)19-8-6-18(17-28)7-9-19/h2-11,16H,12-15H2,1H3,(H,30,34)
PubChem CID	44415743
ChEMBL	CHEMBL213201
IUPHAR	N/A
BindingDB	50190074
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
14721	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
14720	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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