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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	158142-45-1
Molecular formula	C6H10N2O2
IUPAC name	methyl 1,4,5,6-tetrahydropyrimidine-5-carboxylate
Molecular weight	142.158
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	-0.9
Synonyms	SCHEMBL8306627 CHEMBL1189286 L008012 AKOS006358308 CHEMBL538467 1,4,5,6-Tetrahydro-5-pyrimidinecarboxylic acid methyl ester Methyl 1,4,5,6-tetrahydropyrimidine-5-carboxylate 5-pyrimidinecarboxylic acid,1,4,5,6-tetrahydro-,methyl ester BDBM50039839 KB-198515 1,4,5,6-Tetrahydro-pyrimidine-5-carboxylic acid methyl ester; hydrochloride [ Show all ]
Inchi Key	ASEICNBZJHLFCN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C6H10N2O2/c1-10-6(9)5-2-7-4-8-3-5/h4-5H,2-3H2,1H3,(H,7,8)
PubChem CID	10197743
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50039839
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
13061	Muscarinic acetylcholine receptor M1	P12657	Chrm1	Mus musculus (Mouse)	460
13062	Muscarinic acetylcholine receptor M3	Q9ERZ3	Chrm3	Mus musculus (Mouse)	589

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