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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	F3277-0121
Molecular formula	C17H20N4O
IUPAC name	2-ethyl-4-(4-methylpiperazin-1-yl)-[1]benzofuro[3,2-d]pyrimidine
Molecular weight	296.374
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.1
Synonyms	846600-01-9 MolPort-002-615-765 2-ethyl-4-(4-methylpiperazin-1-yl)-[1]benzofuro[3,2-d]pyrimidine J3.528.913E AC1N23JJ STK572319 CHEMBL3741986 2-ethyl-4-(4-methylpiperazin-1-yl)[1]benzofuro[3,2-d]pyrimidine MCULE-9527947415 AKOS005497439 ZINC5216266 2-Ethyl-4-(4-methyl-1-piperazinyl)benzofuro[3,2-d]pyrimidine [ Show all ]
Inchi Key	ASDWPEHJDKKDRB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H20N4O/c1-3-14-18-15-12-6-4-5-7-13(12)22-16(15)17(19-14)21-10-8-20(2)9-11-21/h4-7H,3,8-11H2,1-2H3
PubChem CID	3991311
ChEMBL	CHEMBL3741986
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521840	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
521841	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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