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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL15730
Molecular formula	C26H27N3O3
IUPAC name	2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2-methylphenoxy]-2-phenylacetic acid
Molecular weight	429.52
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.5
Synonyms	L005509 SCHEMBL9127872 [4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-methyl-phenoxy]-phenyl-acetic acid BDBM50284463
Inchi Key	ARHOSMNWKKLMPB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27N3O3/c1-5-22-28-23-17(3)13-18(4)27-25(23)29(22)15-19-11-12-21(16(2)14-19)32-24(26(30)31)20-9-7-6-8-10-20/h6-14,24H,5,15H2,1-4H3,(H,30,31)
PubChem CID	19385623
ChEMBL	CHEMBL15730
IUPHAR	N/A
BindingDB	50284463
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
12480	Type-1 angiotensin II receptor	P34976	AGTR1	Oryctolagus cuniculus (Rabbit)	359
12479	Type-2 angiotensin II receptor	P35351	Agtr2	Rattus norvegicus (Rat)	363

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