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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Type-1 angiotensin II receptor
Species	Oryctolagus cuniculus (Rabbit)
Gene	AGTR1
Synonym	Angiotensin II type-1 receptor AT1
Disease	N/A for non-human GPCRs
Length	359
Amino acid sequence	MMLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLAVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFKIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPSDNVSSSSKKPVPCFEVE
UniProt	P34976
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3948
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL15730
Molecular formula	C26H27N3O3
IUPAC name	2-[4-[(2-ethyl-5,7-dimethylimidazo[4,5-b]pyridin-3-yl)methyl]-2-methylphenoxy]-2-phenylacetic acid
Molecular weight	429.52
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	5.5
Synonyms	[4-(2-Ethyl-5,7-dimethyl-imidazo[4,5-b]pyridin-3-ylmethyl)-2-methyl-phenoxy]-phenyl-acetic acid BDBM50284463 L005509 SCHEMBL9127872
Inchi Key	ARHOSMNWKKLMPB-UHFFFAOYSA-N
Inchi ID	InChI=1S/C26H27N3O3/c1-5-22-28-23-17(3)13-18(4)27-25(23)29(22)15-19-11-12-21(16(2)14-19)32-24(26(30)31)20-9-7-6-8-10-20/h6-14,24H,5,15H2,1-4H3,(H,30,31)
PubChem CID	19385623
ChEMBL	CHEMBL15730
IUPHAR	N/A
BindingDB	50284463
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	14.0 nM	, Bioorg. Med. Chem. Lett., (1995) 5:11:1151	BindingDB,ChEMBL

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