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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000063640
Molecular formula	C19H26ClF3N2O5S
IUPAC name	1-[4-[2-chloro-5-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-3-(oxolan-2-ylmethoxy)propan-2-ol
Molecular weight	486.931
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	2.0
Synonyms	AC1MHBAG HMS1728P03 MLS000863385 HMS2364P11 1-[4-[2-chloro-5-(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-3-(oxolan-2-ylmethoxy)propan-2-ol CHEMBL1531486 MLS000057322 [ Show all ]
Inchi Key	AQNYNIZCMUXTEO-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H26ClF3N2O5S/c20-17-4-3-14(19(21,22)23)10-18(17)31(27,28)25-7-5-24(6-8-25)11-15(26)12-29-13-16-2-1-9-30-16/h3-4,10,15-16,26H,1-2,5-9,11-13H2
PubChem CID	2999219
ChEMBL	CHEMBL1531486
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11953	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
442165	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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