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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL2312685
Molecular formula	C8H16N2O4
IUPAC name	(2S,4R)-2-amino-4-(3-aminopropyl)pentanedioic acid
Molecular weight	204.226
Hydrogen bond acceptor	6
Hydrogen bond donor	4
XlogP	-6.8
Synonyms	BDBM50426287
Inchi Key	APZMCUMLPRUVCO-RITPCOANSA-N
Inchi ID	InChI=1S/C8H16N2O4/c9-3-1-2-5(7(11)12)4-6(10)8(13)14/h5-6H,1-4,9-10H2,(H,11,12)(H,13,14)/t5-,6+/m1/s1
PubChem CID	71574840
ChEMBL	CHEMBL2312685
IUPHAR	N/A
BindingDB	50426287
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
521772	Metabotropic glutamate receptor 1	P23385	Grm1	Rattus norvegicus (Rat)	1199
521771	Metabotropic glutamate receptor 2	P31421	Grm2	Rattus norvegicus (Rat)	872
557620	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
521768	Metabotropic glutamate receptor 3	P31422	Grm3	Rattus norvegicus (Rat)	879
521773	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
521770	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
521769	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915

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