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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	852168-54-8
Molecular formula	C15H17N7O3S2
IUPAC name	N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(1,3,7-trimethyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanylacetamide
Molecular weight	407.467
Hydrogen bond acceptor	9
Hydrogen bond donor	1
XlogP	1.2
Synonyms	F0654-0082 ZINC11758060 AB00684824-01 MLS001167257 N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(1,3,7-trimethyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanylacetamide HMS2981H18 AC1MOSU4 MolPort-003-040-938 CHEMBL1469832 SMR000806012 MCULE-7861555949 AKOS024592631 N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-((2,6,8-trimethyl-5,7-dioxo-5,6,7,8-tetrahydropyrimido[4,5-d]pyrimidin-4-yl)thio)acetamide [ Show all ]
Inchi Key	APVYMSKIUYPWIY-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H17N7O3S2/c1-5-9-19-20-14(27-9)18-8(23)6-26-12-10-11(16-7(2)17-12)21(3)15(25)22(4)13(10)24/h5-6H2,1-4H3,(H,18,20,23)
PubChem CID	3348974
ChEMBL	CHEMBL1469832
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11408	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
11410	Relaxin receptor 2	Q8WXD0	RXFP2	Homo sapiens (Human)	754
11409	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424

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