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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Epidepride
Molecular formula	C16H23IN2O3
IUPAC name	N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-5-iodo-2,3-dimethoxybenzamide
Molecular weight	418.275
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	2.1
Synonyms	Epidepride;N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide Benzamide, N-((1-ethyl-2-pyrrolidinyl)methyl)-5-iodo-2,3-dimethoxy-, (S)- N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-5-iodo-2,3-dimethoxybenzamide (s)-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodo-2,3-dimethoxy-benzamide DTXSID00147929 AC1L3AWQ BRD-K99502674-001-01-5 N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-iodo-2,3-dimethoxybenzamide CHEMBL44237 PDSP2_001484 107188-87-4 BDBM50008782 CHEBI:125687 N-(1-Ethyl-pyrrolidin-2-ylmethyl)-5-iodo-2,3-dimethoxy-benzamide (epidepride) D0C8WL SCHEMBL8961795 [ Show all ]
Inchi Key	APNNSBJHVTUORL-LBPRGKRZSA-N
Inchi ID	InChI=1S/C16H23IN2O3/c1-4-19-7-5-6-12(19)10-18-16(20)13-8-11(17)9-14(21-2)15(13)22-3/h8-9,12H,4-7,10H2,1-3H3,(H,18,20)/t12-/m0/s1
PubChem CID	86101
ChEMBL	CHEMBL44237
IUPHAR	N/A
BindingDB	50008782
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
11154	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
555522	D(2) dopamine receptor	P61168	Drd2	Mus musculus (Mouse)	444
555523	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443

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