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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL172042
Molecular formula	C18H20N2O5
IUPAC name	1-(3,4,5-trimethoxyanilino)-3,4-dihydroisoquinoline-6,7-diol
Molecular weight	344.367
Hydrogen bond acceptor	6
Hydrogen bond donor	3
XlogP	1.9
Synonyms	1-(3,4,5-Trimethoxyanilino)-3,4-dihydroisoquinoline-6,7-diol BDBM50422207
Inchi Key	APHBGWNPNNHZML-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H20N2O5/c1-23-15-7-11(8-16(24-2)17(15)25-3)20-18-12-9-14(22)13(21)6-10(12)4-5-19-18/h6-9,21-22H,4-5H2,1-3H3,(H,19,20)
PubChem CID	135528684
ChEMBL	CHEMBL172042
IUPHAR	N/A
BindingDB	50422207
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
557603	Beta-2 adrenergic receptor	Q8K4Z4	Adrb2	Cavia porcellus (Guinea pig)	418
557604	Beta-2 adrenergic receptor	P07550	ADRB2	Homo sapiens (Human)	413
557602	Thromboxane A2 receptor	P21731	TBXA2R	Homo sapiens (Human)	343

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